Gluten-free dining in New York, NY. Explore the gluten‑free menu, safety notes, and map.
Celiac safety assessment and key features
Twenty-One Grains is that rare Midtown oasis where you can finally exhale—everything on the menu is 100% gluten-free, so you don’t have to play the ingredient-guessing game or worry about stray crumbs. The focus on vibrant grain bowls, inventive wraps, and fresh salads means you’ll find plenty to love, whether you’re after comfort or a nutrient boost. While the website doesn’t mention a celiac owner or chef, the dedicated gluten-free status is front and center, and there’s no sign of wheat anywhere on the menu or in their facility description. For those of us who’ve spent too many lunches double-checking with staff or skipping meals out of fear, it’s almost a relief to know this spot exists—honestly, sometimes peace of mind is the best flavor.
Gluten-Free Options
100% GF Menu
Dedicated Prep Area
Yes - 100% GF facility
Staff Training
Highly knowledgeable
What to expect and popular dishes
Browse gluten‑free options nearby
Recent reviews and experiences
• Twenty-One Grains is a 100% gluten-free restaurant, ensuring a safe environment for celiac diners.
• The establishment emphasizes health-focused, nutrient-dense dishes crafted from fresh ingredients.
• Customer feedback highlights consistent safety practices, with no reports of cross-contamination or gluten exposure.
• Staff are knowledgeable about gluten-free needs, and the kitchen is dedicated to preventing cross-contact.
• The restaurant's reputation is reinforced by its transparency about safety measures and positive community validation.
• Ambiance is modern and welcoming.
• Prices are reasonable for Midtown Manhattan.
• Ideal for health-conscious and gluten-sensitive diners seeking reliable safety.
Important considerations for celiac diners
The restaurant's strict gluten-free operations, combined with staff expertise and dedicated facilities, make it highly suitable for individuals with severe gluten sensitivities or celiac disease.
Is Twenty-One Grains completely gluten-free?
Yes! Twenty-One Grains is a dedicated gluten-free facility with no gluten-containing ingredients on premises.
How does the restaurant prevent cross-contamination?
Dedicated GF kitchen area. Separate fryer for GF items. 100% gluten-free facility.
Is it safe for people with celiac disease?
The restaurant's strict gluten-free operations, combined with staff expertise and dedicated facilities, make it highly suitable for individuals with severe gluten sensitivities or celiac disease.
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