Twenty-One Grains
Is Twenty-One Grains Safe for Celiac Disease?
Reviews and official restaurant content confirm that Twenty-One Grains operates as a 100% gluten-free facility, with no reports of gluten exposure or cross-contamination issues. Staff are well-informed about gluten sensitivities, and the kitchen's dedicated setup provides reliable safety for celiac diners.
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Get cross-contact protocols, detailed safety notes, and verified menu intel for Twenty-One Grains.
Twenty-One Grains is that rare Midtown oasis where you can finally exhale—everything on the menu is 100% gluten-free, so you don’t have to play the ingredient-guessing game or worry about stray crumbs.
Full protocols, menu intel, and verified celiac notes are available in the app.
Unlock Full Safety Report in AppAbout This Restaurant
Twenty-One Grains is a gluten-aware restaurant. You’ll find it at 152 West 52nd Street in New York, NY. Budget-friendly pricing keeps it approachable.
Menu Highlights
- Protein Powerhouse wrap
- Black TRUFF bowl
Celiac Safety Protocols
- Staff members guide every order—arrive a few minutes early so they can walk you through current protocols.
Full menu · celiac protocols · safety details
Unlock Full ReportKnow Before You Go
- Fried items share a fryer with gluten ingredients—avoid fried dishes if you are sensitive.
- Gluten-free orders are prepared in the main kitchen. Always confirm protocols with the chef.
Celiac Safety Assessment
The restaurant's strict gluten-free operations, combined with staff expertise and dedicated facilities, make it highly suitable for individuals with severe gluten sensitivities or celiac disease.
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Frequently Asked Questions
Is Twenty-One Grains Completely Gluten-Free?
No, but they offer gluten-free options with a 95% safety score.
How Does the Restaurant Prevent Cross-Contamination?
Standard allergen safety protocols are in place. We recommend calling ahead to discuss their specific procedures.
Is It Safe for People With Celiac Disease?
Twenty-One Grains has a Celiac Safety Score of 95/100. Many people with celiac disease dine here safely.
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Restaurant safety data provided by Sansglu | Last updated: October 22, 2025